An­ge­bot 151 von 557 vom 12.07.2019, 00:00


RWTH Aachen - I. Physikalisches Institut (IA), AG Biophysik

The research activ­it­ies of the AG Bio­physik aim to estab­lish a fun­da­mental, phys­ics-based under­stand­ing of the func­tion of bio-mac­ro­molec­u­lar sys­tems. In this respect pro­teins and (pro­tein based) mac­ro­molec­u­lar com­plexes, also within in their cel­lu­lar con­text, are of par­tic­u­lar interest for our research top­ics. The exper­i­mental tech­niques used are con­focal fluor­es­cence spec­tro­scopy and single molecule wide-field micro­scopy. Thereby fluor­es­cence cor­rel­a­tion spec­tro­scopy (FCS), sim­ul­tan­eous multi-color detec­tion, and För­ster res­on­ance energy trans­fer (FRET) are employed in our research pro­jects.
We offer the pos­sib­il­it­ies to work with state-of-the-art equip­ment at the inter­face between phys­ics and molecu­lar bio­logy in a highly motiv­ated group and an inter­na­tional and inter­dis­cip­lin­ary work­ing envir­on­ment at the RWTH Aachen Uni­versity and at the Forschung­szen­trum Jülich.

Research Assistant/Associate

Work­ing field:

We are look­ing for an excel­lent and highly motiv­ated postdoc can­did­ate for a DFG fun­ded research pro­ject “Co-trans­la­tional mech­an­isms of pro­tein fold­ing stud­ied on the single molecule level” which will be con­duc­ted in a close col­lab­or­a­tion with the Insti­tute of Com­plex Sys­tems ICS-5 at the Forschung­szen­trum Jülich. You will be part of a team using state-of-the-art equip­ment (TIRF micro­scope for sim­ul­tan­eous dual color ima­ging, con­focal micro­scope with pulsed excit­a­tion and multi-chan­nel detec­tion) which invest­ig­ates struc­tural and dynam­ical prop­er­ties of pro­teins and pro­tein com­plexes. This includes to applic­a­tion of nano-aper­tures like zero mode wave­guides (ZMWs) to study pro­tein lig­and inter­ac­tions at physiolo­gical rel­ev­ant con­cen­tra­tions on single molecule level. The res­ults of your research are expec­ted to be pub­lished in inter­na­tional peer reviewed journ­als.


Applic­ants must have a doc­tor­ate/Ph.D. or equi­val­ent.
  • A higher degree in Phys­ics, Chem­istry or Bio­chem­istry and a Doc­tor­ate in a related field
  • Extens­ive know­ledge of high res­ol­u­tion fluor­es­cence micro­scopy and spec­tro­scopy
  • Com­pre­hens­ive exper­i­ence in con­duct­ing research pro­jects in struc­tural bio­logy by using fluor­es­cence based single molecule tech­niques.
  • The abil­ity to com­mu­nic­ate and work effect­ively in an inter­dis­cip­lin­ary an inter­na­tional team
  • A struc­tured and sys­tem­atic approach to prob­lem solv­ing

What we of­fer:

The pos­i­tion is 3 years and is to be filled as soon as pos­sible. This is a full-time pos­i­tion.

The salary cor­res­ponds to level EG 13 TV-L.

RWTH Aachen Uni­versity is cer­ti­fied as a "Fam­ily-Friendly Uni­versity". We wel­come applic­a­tions from all suit­ably qual­i­fied can­did­ates regard­less of gender. We par­tic­u­larly wel­come and encour­age applic­a­tions from women, dis­abled per­sons and eth­nic minor­ity groups, recog­niz­ing they are under­rep­res­en­ted across RWTH Aachen Uni­versity. The prin­ciples of fair and open com­pet­i­tion apply and appoint­ments will be made on merit. RWTH Aachen is an equal oppor­tun­it­ies employer. We there­fore ask you not to include a photo in your applic­a­tion. For inform­a­tion on the col­lec­tion of per­sonal data pur­su­ant to Art­icles 13 and 14 of the Gen­eral Data Pro­tec­tion Reg­u­la­tion (GDPR), please visit:

How to ap­ply:

For further details, please contact
Prof. Dr. Jörg Fitter
Tel.: +49 (0) 241 80 27209

For further information, please visit our website at:

Please send your application by July 15, 2019 to
Prof. Dr. J. Fitter
I. Physikalisches Institut (IA), AG Biophysik
RWTH Aachen
Sommerfeldstrasse 14
D-52056 Aachen

You can also send your application via email to Please note, however, that communication via unencrypted e-mail poses a threat to confidentiality as it is potentially vulnerable to unauthorized access by third parties.