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Tech­ni­sche Uni­ver­sität Ber­lin - Fac­ulty II - Insti­tute of Chem­istry / Max-Vol­mer-Labor­at­ory of Bio­phys­ical Chem­istry

Research Assist­ant - 0.5 work­ing time - salary grade E13 TV-L Ber­liner Hoch­schu­len

Work­ing field:

Research on struc­ture-func­tion rela­tion­ships of caroten­oid-bind­ing pro­teins, espe­cially of the Orange Caroten­oid Pro­tein (OCP)
  • Gen­er­a­tion of cDNA con­structs for pro­tein and caroten­oid pro­duc­tion in bac­teria by molecu­lar-bio­lo­gical meth­ods, site-dir­ec­ted muta­gen­esis, recom­bin­ant PCR
  • Caroten­oid and pro­tein pro­duc­tion in bac­teria, chro­ma­to­graphic puri­fic­a­tion and pro­tein ana­lyt­ics
  • Mass spec­tro­metry on caroten­oids and caroten­oid-bind­ing pro­teins
  • Iso­tope labeling of caroten­oids and caroten­oid-bind­ing pro­teins for spec­tro­scopic and struc­tural stud­ies
  • Chro­ma­to­graphic and spec­tro­scopic stud­ies on pro­tein-pro­tein inter­ac­tions
  • UV/Vis absorp­tion, CD and Fluor­es­cence life­time spec­tro­scopy
  • Small-angle X-ray and neut­ron scat­ter­ing exper­i­ments (SAXS, SANS), quasielastic neut­ron scat­ter­ing (QENS) for determ­in­a­tion of struc­ture and dynam­ics
  • Func­tional stud­ies on caroten­oid-bind­ing pro­teins
  • Writ­ing/edit­ing of sci­entific manuscripts for pub­lic­a­tion, con­fer­ence and pro­ject reports

Require­ments:

  • Suc­cess­fully com­pleted uni­versity degree (Mas­ter, Dip­lom oder Äqui­val­ent) in Bio­phys­ics, Bio­chem­istry, Bio­lo­gical Chem­istry or Chem­istry
  • Exper­i­ence in molecu­lar bio­logy, pro­tein bio­chem­istry and chro­ma­to­graphic tech­niques (FPLC, HPLC, SEC, HIC)
  • Expert­ise in spec­tro­scopic tech­niques (UV-Vis absorp­tion spec­tro­scopy, fluor­es­cence spec­tro­scopy
Desired:
  • Exper­i­ence with mass spec­tro­met­ric ana­lysis of pro­teins and bioor­ganic molecules (ESI-MS, LC-MS), basic skills in NMR struc­ture determ­in­a­tion of Pro­teins
  • the abil­ity to work in a team and to cooper­ate
  • flu­ent Eng­lish (oral and writ­ten), and fun­da­mental know­ledge of Rus­sian lan­guage are advant­age­ous

How to ap­ply:

Please send your writ­ten applic­a­tion with the ref­er­ence num­ber and the usual doc­u­ments to Tech­nis­che Uni­versität Ber­lin - Der Präsid­ent - Fakultät II, Institut für Chemie, Max-Volmer-Laboratorium für Biophysikalische Chemie, Prof. Dr. Friedrich, Sekr. PC 14, Straße des 17. Juni 135, 10623 Berlin or by e-mail to friedrich@chem.tu-berlin.de.

To ensure equal oppor­tu­nit­ies bet­ween women and men, app­li­ca­ti­ons by women with the requi­red qua­li­fi­ca­ti­ons are expli­citly desi­red.
Qua­li­fied indi­vi­du­als with disa­bi­li­ties will be favo­red. The TU Berlin values the diversity of its members and is committed to the goals of equal opportunities.

Please send cop­ies only. Ori­gi­nal docu­ments will not be retur­ned.